Welcome to Dr. Bing Zhang’s Lab at the Baylor College of Medicine. We develop and use integrative bioinformatics approaches to extract biological meanings from experimental data and generate hypotheses for experimental validation. Please explore our website to learn more about our people and our research.

Lab News

[2016-11] Yongchao’s paper Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes has been published in Scientific Reports. Congratulations, Yongchao!

[2016-11]  From Proteomic Data Improves Gene Function Predictions, CPTAC Team Finds.

[2016-11] Jing’s paper Proteome profiling outperforms transcriptome profiling for co-expression based gene function prediction has been published in Molecular & Cellular Proteomics. Congratulations, Jing!

[2016-11] Zhang Lab welcomes visiting scholar Professor Sang-Won Lee from the Korea University and his student Jeong Eun So (Jessie). Sang-Won and Jessie will be staying with us until January 2017.

[2016-10] Baylor welcomes new McNair Scholar, Dr. Bing Zhang

[2016-08] Zhang Lab has moved from VUMC to BCM.

[2016-07] Congratulations to Matt on successfully defending his Master’s thesis!

[2016-06] Congratulations to Jason on successfully defending his Master’s thesis!

[2015-12] Qi’s paper Integrative omics analysis reveals post-transcriptionally enhanced protective host response in colorectal cancers with microsatellite instability has been published in the Journal of Proteome Research. The paper introduces a resampling-based regression method that integrates transcriptomic and proteomic datasets to accurately identify genes subject to differential post-transcriptional regulation. Applying the method to the TCGA colorectal tumors revealed post-transcriptionally innitiated protective host response in cancers with microsatellite instability.

[2015-12] Xiaojing’s paper proBAMsuite, a bioinformatics framework for genome-based representation and analysis of proteomics data has been published in Molecular & Cellular Proteomics (MCP). This paper introduces protein BAM (proBAM), a new file format for organizing peptide spectrum matches (PSMs) within the context of the genome. The proBAMsuite includes two R packages, proBAMr and proBAMtools, for generating and analyzing proBAM files, respectively. The study demonstrated the utility of the proBAMsuite in facilitating efficient genome-based sharing, interpretation and integration of proteomics and proteogenomics data.

[2015-12] Matt received the 2015 DBMI Research Staff Excellence Award. Congratulations!

[2015-12] Junhui Shen M.S. joined the group as a visiting scholar. Junhui is an Associate Professor at the Information Center of the Beijing University of Chinese Medicine. Welcome to the group!

[2015-10] QCB student Mary Benton joined the group for a research rotation. Welcome, Mary!

[2015-08] MSTP student Patrick Wu joined the group for a research rotation. Welcome, Patrick!